瑞禧生物货号:Ruixi-A629283
化学名称:4-(4-Aminophenoxy)-2-pyridinecarboxamide
同义名称:4-(2-Carbamoyl-4-pyridyloxy)aniline; 4-(4-Aminophenoxy)picolinamide
CAS号:284462-80-2
分子式:C₁₂H₁₁N₃O₂
Appearance:Brown to Dark Brown Solid
Melting Point:>190ºC (dec.)
分子量:229.23
Storage:-20°C, Inert atmosphere, Light sensitive
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Light Sensitive
产品类别:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用:4-(4-Aminophenoxy)-2-pyridinecarboxamide is an intermediate in the synthesis of N-Desmethyl Sorafenib (D293290). N-Desmethyl Sorafenib is a metabolite of Sorafenib (S676850) and has anti-proliferative activity in human breast cancer cells.
参考文献:Cui, P.H., et al.: Biochem. Pharmacol., 86, 419 (2013); Ghassabian, S., et al.: Biochem. Pharmacol., 84, 215 (2012)
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