瑞禧生物货号:Ruixi-B432175
化学名称:N,N’-Bis(2,2’-dithiosalicyl)hydrazide
同义名称:NSC 704783; 12,13,26,27-Tetrahydrotetrabenzo[c,i,m,s][1,2,11,12,6,7,16,17]tetrathiatetraazacycloeicosine-11,14,25,28-tetrone;
CAS号:292615-40-8
分子式:C₂₈H₂₀N₄O₄S₄
Appearance:White Powder
Melting Point:148°C dec.
分子量:604.74
产品类别:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
产品应用:N,N’-Bis(2,2’-dithiosalicyl)hydrazide is a selective inhibitor of HIV-1 integrase. Has no other effect on other retroviral targets, including reverse transcriptase, protease, and virus attachement, and exhibits no detectable activity against human topoisomerases I and II at concentrations that effectively inhibit integrase.
参考文献:Neamati, N., et al.: J. Med. Chem., 45, 5661 (2003)
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